Temperature-induced ultraviolet absorption changes of heavy meromyosin

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Interaction of Heavy Meromyosin with Substrate I. DIFFERENCE IN ULTRAVIOLET ABSORPTION SPECTRUM BETWEEN HEAVY MEROMYOSIN

Difference spectra induced by ATP and its analogues of the ultraviolet absorption of heavy meromyosin around 280 rnp were measured by the double cell method. The difference spectrum induced by ATP showed two peaks, at 281 and 289 rnp, and a shoulder near 300 mp. The maximum value of the difference molar extinction coefficient, AE, at 289 mp, was 5000 f 300 Me1 cm-l. The difference spectrum caus...

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Interaction of heavy meromyosin with substrate. I. Difference in ultraviolet absorption spectrum between heavy meromyosin and its Michaelis-Menten complex.

Difference spectra induced by ATP and its analogues of the ultraviolet absorption of heavy meromyosin around 280 rnp were measured by the double cell method. The difference spectrum induced by ATP showed two peaks, at 281 and 289 rnp, and a shoulder near 300 mp. The maximum value of the difference molar extinction coefficient, AE, at 289 mp, was 5000 f 300 Me1 cm-l. The difference spectrum caus...

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The degradation of heavy meromyosin by trypsin.

Consden, R. & Gordon, A. H. (1948). Nature, Lond., 162, 180. Dixon, J. S. & Lipkin, D. (1954). Analyt. Chem. 26, 1092. Elliott, S. D. (1962). Nature, Lond., 193, 1105. Foster, A. B., Horton, D. & Stacey, M. (1957). J. chem. Soc. p. 81. Gelotte, B. (1960). J. Chromat. 3, 330. Hanahan, D. J. & Olley, J. N. (1958). J. biol. Chem. 231, 813. Hanes, C. S. & Isherwood, F. A. (1949). Nature, Lond., 164...

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The substructure of heavy meromyosin. The effect of Ca2+ and Mg2+ on the tryptic fragmentation of heavy meromyosin.

Heavy meromyosin, obtained by tryptic digestion of myosin, containing two main polypeptides whose masses were estimated as 81,000 and 74,000 dlatons from Na dodecyl-SO4 polyacrylamide gel electrophoresis, was further digested with trypsin. The Ca2+-activated ATPase activity remainded unchanged and the K+-EDTA activity increased while various smaller fragments were formed. The formation of some ...

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Changes in ultraviolet absorption produced by alteration of protein conformation.

Transfer of an aromatic chromophore from the interior of a protein into the water solvent upon denaturation of the protein produces an absorption change throughout the ultraviolet region, 215 to 320 rnp, approximately 6 times the magnitude of that produced by transfer of the same chromophore from 20% ethylene glycol into water. In the 230 rnE.1 wave length region, the transfer of an indole chro...

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ژورنال

عنوان ژورنال: FEBS Letters

سال: 1984

ISSN: 0014-5793

DOI: 10.1016/0014-5793(84)80196-9